Hazardous Drugs - Contamination, Risk of Exposure and Prevention

Hazardous drugs are medicines that have theHazardous drugs are required to be handled with
tendency to create health disorders likeproper care in order to avoid health disorders.
genotoxicity, carcinogenicity and teratogenicity. InOccupational Safety and Health Administration
simple words, these medicines can cause mutationhave published guidelines for safe handling of
or change of genetic material, cancerous growthHazardous drugs. Using personal protective
in cells, defects in foetal development andequipment like gloves, gowns, caps, and face
infertility. The different categories of Hazardousmasks can protect the nurses, physicians and
drugs are cytotoxic agents, antineoplastics,other people handling medicines during their
immunosuppressive agents, biological agents andpreparation, administration and transfer. Drug
antiviral agents. Due to the adverse health effectspreparation in Biological Safety cabinets can
that can be caused by these medicines, severalprevent contamination and occupational exposure
scientific research organizations have publishedto toxic elements contained in the medicines. Use
guidelines on the safe handling of the variousof syringes, IV sets and infusion sets having Luer
medicines.lock fittings can help leakage of medicine.
There are various ways in which people employedAntineoplastic agents used in the treatment of
in the field of medicines can be exposed to thecancer are beneficial to the patients. However
disastrous effects of the toxic medications. Healthexposure to these medications can cause health
hazards having mild to severe complications cancomplications. Nurses, hospital staff like laundry
be caused by inhalation of vapors and absorptionworkers, waste handlers, and custodial workers
of chemical compounds into skin by accidentalare all exposed to the medicines and the harmful
contact. Leakage and spills during theelements contained in them during the treatment
manufacture, preparation, administration, storageof patients. Use of closed system drug transfer
and transfer of medicines and other chemicaldevices can help reduce the occupational
compounds can contaminate work surfaces andexposure and resulting health hazards.
expose healthcare personnel to health disorders.