INSTEAD SCIENCES, INC.Announces Plans For Launch Of MICROBICIDE EXPECTED To Prevention STD'S & HIV

LA JOLLA, CA (March 24, 2008)- Today, Insteadthe product later this year. It is, to date, the only
Sciences, Inc. announced that its microbicidalmicrobicidal candidate that has been cleared for
personal lubricant, Amphora, which has beenthis application. The promising results from clinical
cleared as safe for human use by the FDA, hasstudies that indicate Amphora may help prevent
shown promising results in clinical studies to alsothe spread of STD's and HIV indicate an even
prevent the contraction of certain sexuallygreater health benefit from its use.
transmitted diseases, including HSV (Herpes),According to a study conducted by Mt. Sinai
gonorrhea, Chlamydia, and HIV. In light of theresearchers, Amphora has the ability to reduce
revealing report published earlier this month by thethe infection rate of the Herpes Simplex Virus
Centers for Disease Control (CDC) stating that(HSV) by 99% after 30 minutes of exposure to
one in four teenagers has a sexually transmittedthe microbicide. Amphora works as a bio-adhesive
infection, the announcement of a microbicide"acid buffering" gel that coats the vaginal wall and
which may prevent the spread of these diseasescervix, helping maintain a woman's natural pH level
is very encouraging.between 3.8 and 4.2, a level that has been proven
"Preventing the spread of STD's and HIV isin early clinical testing to render sperm immobile
unfortunately one of the largest ongoing battlesand to inactivate most STI-causing organisms,
of our time, as is evidenced by last week'sincluding herpes, Chlamydia, HSV, gonorrhea, and
alarming CDC report. With the youth of ourHIV.
country at a greater risk for contracting sexuallyIn light of the knowledge that many STD's,
transmitted diseases, it is becoming increasinglyincluding HIV itself, are extremely fragile
important for us to develop preventive,(effectively killed by lemon juice, saliva, or even
over-the-counter products. Fortunately, researchexposure to air ), the observations made in the
is proving this to be a real possibility in the formMt. Sinai study bolster the hypothesis that
of topical microbicides," explains Joseph Pike,Amphora will have a similar effect in significantly
President/CEO of Instead Sciences Inc.reducing the infection rate of HIV and other
Amphora has already been FDA cleared for use inSTD's, as was the case with the HSV testing.
humans as a lubricant, and Instead plans to launch