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INSTEAD SCIENCES, INC.Announces Plans For Launch Of MICROBICIDE EXPECTED To Prevention STD'S & HIV

LA JOLLA, CA (March 24, 2008)- Today, Insteadto launch the product later this year. It
Sciences, Inc. announced that itsis, to date, the only microbicidal candidate
microbicidal personal lubricant, Amphora,that has been cleared for this application.
which has been cleared as safe for human useThe promising results from clinical studies
by the FDA, has shown promising results inthat indicate Amphora may help prevent the
clinical studies to also prevent thespread of STD's and HIV indicate an even
contraction of certain sexually transmittedgreater  health  benefit  from  its  use.
diseases, including HSV (Herpes), gonorrhea,
Chlamydia, and HIV. In light of theAccording to a study conducted by Mt. Sinai
revealing report published earlier this monthresearchers, Amphora has the ability to
by the Centers for Disease Control (CDC)reduce the infection rate of the Herpes
stating that one in four teenagers has aSimplex Virus (HSV) by 99% after 30 minutes
sexually transmitted infection, theof exposure to the microbicide. Amphora
announcement of a microbicide which mayworks as a bio-adhesive "acid buffering" gel
prevent the spread of these diseases is verythat coats the vaginal wall and cervix,
encouraging.helping maintain a woman's natural pH level
between 3.8 and 4.2, a level that has been
"Preventing the spread of STD's and HIV isproven in early clinical testing to render
unfortunately one of the largest ongoingsperm immobile and to inactivate most
battles of our time, as is evidenced by lastSTI-causing organisms, including herpes,
week's alarming CDC report. With the youthChlamydia,  HSV,  gonorrhea,  and  HIV.
of our country at a greater risk for
contracting sexually transmitted diseases, itIn light of the knowledge that many STD's,
is becoming increasingly important for us toincluding HIV itself, are extremely fragile
develop preventive, over-the-counter(effectively killed by lemon juice, saliva,
products. Fortunately, research is provingor even exposure to air ), the observations
this to be a real possibility in the form ofmade in the Mt. Sinai study bolster the
topical microbicides," explains Joseph Pike,hypothesis that Amphora will have a similar
President/CEO  of  Instead  Sciences  Inc.effect in significantly reducing the
infection rate of HIV and other STD's, as was
Amphora has already been FDA cleared for usethe case with the HSV testing.
in humans as a lubricant, and Instead plans



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